Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AIMP2 | Q13155 | 3/20 | 0.46 |
| ▸ | GRM7 | Q14831 | 3/20 | 0.41 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.35 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.35 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.35 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20182785 | 0.87 | AIMP2 (0.52) | AIMP2GRM7PSMB5CYP2C19CYP1A2 | |
| SCHEMBL29909634 | 0.83 | GRM7 (0.63) | GRM7DGAT2BRD4 | |
| SCHEMBL21559932 | 0.83 | GRM7 (0.63) | GRM7DGAT2BRD4 | |
| SCHEMBL20182869 | 0.80 | AIMP2 (0.56) | AIMP2GRM7PSMB5CYP2C19CYP1A2 | |
| SCHEMBL20182939 | 0.78 | PSMB5 (0.50) | AIMP2PSMB5CYP2C19CYP1A2CYP2D6 | |
| SCHEMBL20182838 | 0.77 | AIMP2 (0.51) | AIMP2GRM7PSMB5CYP2C19CYP1A2 | |
| SCHEMBL20182835 | 0.74 | GRM7 (0.62) | GRM7DGAT2KMT2AALDH1A1TAS1R3 | |
| SCHEMBL20182778 | 0.73 | AIMP2 (0.49) | AIMP2GRM7PSMB5CYP2C19CYP1A2 | |
| SCHEMBL20183017 | 0.73 | AIMP2 (0.49) | AIMP2GRM7PSMB5CYP2C19CYP1A2 | |
| SCHEMBL20182998 | 0.72 | AIMP2 (0.47) | AIMP2GRM7PSMB5KMT2ASIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018092921-A1 | MGLUR7 AGONIST COMPOUNDS FOR TREATING MGLUR7- REGULATED DISEASES, DISORDERS, OR CONDITIONS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2018-05-24 | — | — | WO | disclosed |