Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | PGR | P06401 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 7/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2018313 | 0.89 | HPGD (0.54) | HPGDALDH1A1MAPK1LMNACYP1A2 | |
| SCHEMBL4607568 | 0.84 | HPGD (0.54) | HPGDALDH1A1MAPK1LMNACYP1A2 | |
| SCHEMBL3359451 | 0.82 | HPGD (0.53) | HPGDALDH1A1MAPK1LMNACYP1A2 | |
| SCHEMBL4339862 | 0.80 | HPGD (0.48) | HPGDALDH1A1MAPK1LMNACYP1A2 | |
| SCHEMBL4339860 | 0.79 | HPGD (0.51) | HPGDALDH1A1MAPK1LMNACYP1A2 | |
| SCHEMBL9447781 | 0.78 | HPGD (0.59) | HPGDALDH1A1MAPK1LMNACYP1A2 | |
| SCHEMBL28452372 | 0.77 | HPGD (0.55) | HPGDALDH1A1MAPK1LMNACYP1A2 | |
| SCHEMBL23222467 | 0.75 | HPGD (0.46) | HPGDALDH1A1MAPK1LMNACYP1A2 | |
| SCHEMBL2419965 | 0.75 | LMNA (0.58) | HPGDALDH1A1MAPK1LMNACYP1A2 | |
| SCHEMBL9447785 | 0.75 | HPGD (0.57) | HPGDALDH1A1MAPK1LMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230244000-A1 | MULTIFUNCTIONAL CROSSLINKING AGENTS AND OPHTHALMIC DEVICES FORMED THEREFROM | JPMORGAN CHASE BANK, N.A., AS SUCCESSOR AGENT | 2023-08-03 | — | — | US | disclosed |