⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12100744 | 1.00 | — | — | |
| SCHEMBL12172364 | 0.85 | LMNA (0.38) | — | |
| SCHEMBL22909935 | 0.85 | — | — | |
| SCHEMBL12099755 | 0.85 | — | — | |
| SCHEMBL2014520 | 0.83 | — | — | |
| SCHEMBL2015869 | 0.80 | — | — | |
| SCHEMBL2014253 | 0.80 | — | — | |
| SCHEMBL22909728 | 0.80 | PRKCZ (0.42) | — | |
| SCHEMBL2017414 | 0.78 | — | — | |
| SCHEMBL2015312 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11981696-B2 | Fluoro-pyridinone phosphates and boronates useful as antibacterial agents | PFIZER INC. (US) | 2024-05-14 | — | — | US | disclosed |
| EP-2683689-B1 | FLUORO-PYRIDINONE DERIVATIVES USEFUL AS ANTIBACTERIAL AGENTS | PFIZER (US) | 2017-04-12 | — | — | EP | disclosed |
| US-8779148-B2 | Fluoro-pyridinone derivatives useful as antibacterial agents | PFIZER INC. (US) | 2014-07-15 | — | — | US | disclosed |
| US-20140057919-A1 | FLUORO-PYRIDINONE DERIVATIVES USEFUL AS ANTIBACTERIAL AGENTS | PFIZER INC. (US) | 2014-02-27 | — | — | US | disclosed |
| US-8624034-B2 | Fluoro-pyridinone derivatives useful as antibacterial agents | PFIZER INC. (US) | 2014-01-07 | — | — | US | disclosed |
| US-20120232083-A1 | FLUORO-PYRIDINONE DERIVATIVES USEFUL AS ANTIBACTERIAL AGENTS | PFIZER INC | 2012-09-13 | — | — | US | disclosed |
| WO-2012120397-A1 | FLUORO-PYRIDINONE DERIVATIVES USEFUL AS ANTIBACTERIAL AGENTS | PFIZER INC. (US) | 2012-09-13 | — | — | WO | disclosed |
| WO-2011073845-A1 | N-LINKED HYDROXAMIC ACID DERIVATIVES USEFUL AS ANTIBACTERIAL AGENTS | PFIZER INC. (US) | 2011-06-23 | — | — | WO | disclosed |