SCHEMBL20183301

SCHEMBL20183301

CCCCCCCCCCCCCCCCCCCCCC(=O)OC(=O)C(O)CO.O=C(O)CCCCCCCCCCCCCCCCCCC(=O)O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.54
KMT2A Q03164 2/20 0.54
KDM4E B2RXH2 1/20 0.54
DUSP3 P51452 1/20 0.54
LMNA P02545 1/20 0.54
GPR84 Q9NQS5 7/20 0.53
PPARG P37231 7/20 0.53
PPARD Q03181 7/20 0.53
PPARA Q07869 7/20 0.53
HDAC11 Q96DB2 5/20 0.53
TSHR P16473 4/20 0.53
PTPN1 P18031 3/20 0.53
ALDH1A1 P00352 2/20 0.53
TLR2 O60603 2/20 0.53
TDP1 Q9NUW8 2/20 0.53
FABP4 P15090 2/20 0.53
FFAR4 Q5NUL3 2/20 0.53
SLC22A6 Q4U2R8 1/20 0.53
SLC22A8 Q8TCC7 1/20 0.53
ESR1 P03372 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Octanoic Acid SCHEMBL23668206 1.00 MEN1 (0.54) MEN1KMT2AKDM4EDUSP3LMNA
Stearic Acid SCHEMBL7999492 1.00 MEN1 (0.54) MEN1KMT2AKDM4EDUSP3LMNA
Stearic Acid SCHEMBL6366300 1.00 MEN1 (0.54) MEN1KMT2AKDM4EDUSP3LMNA
Behenic Acid SCHEMBL626540 1.00 MEN1 (0.54) MEN1KMT2AKDM4EDUSP3LMNA
Octanoic Acid SCHEMBL22720164 0.95 GPR84 (0.52) MEN1KMT2AKDM4EDUSP3LMNA
SCHEMBL16041 0.94 LMNA (0.60) MEN1KMT2AKDM4EDUSP3LMNA
SCHEMBL2119135 0.94 LMNA (0.60) MEN1KMT2AKDM4EDUSP3LMNA
SCHEMBL21685975 0.94 LMNA (0.60) MEN1KMT2AKDM4EDUSP3LMNA
SCHEMBL3804 0.94 LMNA (0.60) MEN1KMT2AKDM4EDUSP3LMNA
SCHEMBL62799 0.94 LMNA (0.60) MEN1KMT2AKDM4EDUSP3LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108137813-B Cured silicone particles and cosmetic materials incorporating cured silicone particles therein 陶氏东丽株式会社 2020-12-29 CN disclosed
US-10731009-B2 Cured silicone particles and cosmetic incorporating same therein DOW TORAY CO., LTD. (JP) 2020-08-04 US disclosed
EP-3327064-B1 CURED SILICONE PARTICLES AND COSMETIC INCORPORATING SAME THEREIN DOW TORAY CO LTD (JP) 2020-04-15 EP disclosed
US-20180215877-A1 CURED SILICONE PARTICLES AND COSMETIC INCORPORATING SAME THEREIN DOW TORAY CO., LTD. (JP) 2018-08-02 US disclosed
CN-108137813-A Cured silicone particle and the beauty treatment material for wherein combining cured silicone particle 道康宁东丽株式会社 2018-06-08 CN disclosed
EP-3327064-A1 CURED SILICONE PARTICLES AND COSMETIC INCORPORATING SAME THEREIN Dow Corning Toray Co., Ltd. (JP) 2018-05-30 EP disclosed