Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 7/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | THRA | P10827 | 6/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | KLK1 | P06870 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | FOXO1 | Q12778 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL372605 | 0.93 | THRB (0.47) | TSHRALDH1A1CYP3A4HPGDTHRB | |
| SCHEMBL372606 | 0.93 | THRB (0.47) | TSHRALDH1A1CYP3A4HPGDTHRB | |
| SCHEMBL10605595 | 0.85 | TSHR (0.50) | TSHRALDH1A1CYP3A4HPGDTHRB | |
| SCHEMBL11171075 | 0.83 | CYP3A4 (0.35) | TSHRCYP3A4THRBTHRAMEN1 | |
| SCHEMBL447953 | 0.78 | THRB (0.51) | TSHRALDH1A1CYP3A4HPGDTHRB | |
| SCHEMBL10883638 | 0.76 | CYP3A4 (0.34) | TSHRCYP3A4THRBTHRAMEN1 | |
| SCHEMBL11566263 | 0.76 | KLK1 (0.41) | ALDH1A1THRBTHRAMEN1KMT2A | |
| SCHEMBL372258 | 0.75 | THRB (0.49) | TSHRALDH1A1CYP3A4HPGDTHRB | |
| SCHEMBL372731 | 0.75 | THRB (0.56) | TSHRALDH1A1CYP3A4HPGDTHRB | |
| SCHEMBL372732 | 0.75 | THRB (0.56) | TSHRALDH1A1CYP3A4HPGDTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3327472-B1 | HOLOGRAPHIC OPTICAL ELEMENT AND PRODUCTION METHOD THEREFOR | KONICA MINOLTA INC (JP) | 2019-10-30 | — | — | EP | disclosed |
| US-20180217311-A1 | HOLOGRAPHIC OPTICAL ELEMENT AND METHOD FOR PRODUCING THE SAME | Konica Minolta, Inc. (JP) | 2018-08-02 | — | — | US | disclosed |
| EP-3327472-A1 | HOLOGRAPHIC OPTICAL ELEMENT AND PRODUCTION METHOD THEREFOR | Konica Minolta, Inc. (JP) | 2018-05-30 | — | — | EP | disclosed |