Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLK1 | P06870 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 7/20 | 0.41 |
| ▸ | THRA | P10827 | 6/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11577842 | 0.95 | KLK1 (0.44) | KLK1THRBTHRAMCHR1HRH3 | |
| SCHEMBL483839 | 0.91 | MCHR1 (0.43) | KLK1THRBTHRAMCHR1HRH3 | |
| SCHEMBL11022560 | 0.91 | MCHR1 (0.43) | KLK1THRBTHRAMCHR1HRH3 | |
| SCHEMBL2349299 | 0.84 | KLK1 (0.39) | KLK1THRBTHRAHRH3MEN1 | |
| SCHEMBL21077306 | 0.79 | THRB (0.34) | KLK1THRBTHRAHRH3CA2 | |
| SCHEMBL26290173 | 0.79 | KDM4E (0.38) | THRBTHRAMEN1KMT2AKDM4E | |
| SCHEMBL2679538 | 0.77 | THRA (0.41) | KLK1THRBTHRAHRH3ALDH1A1 | |
| SCHEMBL23332926 | 0.76 | THRB (0.51) | THRBTHRAMEN1KMT2ACA2 | |
| SCHEMBL20183966 | 0.76 | TSHR (0.45) | KLK1THRBTHRAMEN1KMT2A | |
| SCHEMBL27574370 | 0.76 | KDM4E (0.50) | KLK1THRBTHRAHRH3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4178410-A | POLYURETHANE AND A SULFONE | Meisei Chemical Works, Inc. (JP) | 1979-12-11 | — | — | US | disclosed |
| US-4104259-A | Fireproof polyesters from brominated dihydroxy alkoxy-diphenyl sulfones | TOYO BOSEKI KABUSHIKI KAISHA (JP) | 1978-08-01 | — | — | US | disclosed |