SCHEMBL20183973

SCHEMBL20183973

C=C(C)C(=O)Oc1cccc(N=C=S)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 1/20 0.46
KMT2A Q03164 5/20 0.40
ATM Q13315 1/20 0.40
CYP3A4 P08684 2/20 0.37
LMNA P02545 1/20 0.37
MIF P14174 1/20 0.37
ACHE P22303 1/20 0.35
MEN1 O00255 3/20 0.35
P2RY6 Q15077 2/20 0.35
ALDH1A1 P00352 1/20 0.35
MAPT P10636 1/20 0.35
ALOX15 P16050 1/20 0.35
MITF O75030 1/20 0.34
CYP2D6 P10635 1/20 0.34
HIF1A Q16665 1/20 0.34
HTR3E A5X5Y0 1/20 0.33
HTR3B O95264 1/20 0.33
HTR3A P46098 1/20 0.33
HTR3D Q70Z44 1/20 0.33
HTR3C Q8WXA8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL633163 0.87 ELANE (0.43) ELANEKMT2AATMCYP3A4LMNA
SCHEMBL14689928 0.86 ELANE (0.47) ELANEKMT2AATMCYP3A4LMNA
SCHEMBL7765430 0.83 ELANE (0.51) ELANEKMT2AATMLMNAMIF
SCHEMBL20183951 0.79 MIF (0.39) KMT2ACYP3A4MIFACHEMEN1
SCHEMBL218655 0.79 ELANE (0.56) ELANEKMT2AATMCYP3A4LMNA
SCHEMBL27461707 0.79 MIF (0.41) KMT2ACYP3A4LMNAMIFMEN1
SCHEMBL14173263 0.75 ELANE (0.53) ELANEKMT2AATMCYP3A4LMNA
SCHEMBL5796149 0.75 MIF (0.44) KMT2ACYP3A4LMNAMIFMEN1
SCHEMBL379060 0.75 ELANE (0.51) ELANEKMT2AATMCYP3A4LMNA
SCHEMBL14173262 0.75 ELANE (0.51) ELANEKMT2AATMCYP3A4LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10647784-B2 Resin and surface protective plate or automotive material SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2020-05-12 US disclosed
EP-3327052-B1 RESIN AND SURFACE PROTECTION PLATE OR AUTOMOTIVE MATERIAL SUMITOMO CHEMICAL CO (JP) 2020-03-04 EP disclosed
CN-107849199-B Resin, surface protective plate, or automobile material 住友化学株式会社 2019-12-27 CN disclosed
US-20180215837-A1 RESIN AND SURFACE PROTECTIVE PLATE OR AUTOMOTIVE MATERIAL SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-08-02 US disclosed
EP-3327052-A1 RESIN AND SURFACE PROTECTION PLATE OR AUTOMOTIVE MATERIAL Sumitomo Chemical Company, Ltd. (JP) 2018-05-30 EP disclosed
CN-107849199-A Resin and surface protection board or materials used in auto manufacturing 住友化学株式会社 2018-03-27 CN disclosed