SCHEMBL7765430

SCHEMBL7765430

C=C(C)C(=O)Oc1ccc(N=C=S)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 2/20 0.51
KMT2A Q03164 3/20 0.48
ATM Q13315 1/20 0.48
HSD17B10 Q99714 1/20 0.41
P2RY6 Q15077 3/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
MIF P14174 1/20 0.38
KEAP1 Q14145 1/20 0.36
NFE2L2 Q16236 1/20 0.36
LMNA P02545 1/20 0.35
MAPT P10636 2/20 0.35
POLB P06746 2/20 0.33
APEX1 P27695 1/20 0.33
HTT P42858 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
RAD1 O60671 1/20 0.33
F2 P00734 1/20 0.33
PRSS1 P07477 1/20 0.33
PRSS2 P07478 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL633697 0.87 ELANE (0.51) ELANEKMT2AATMLMNAMAPT
SCHEMBL20183973 0.83 ELANE (0.46) ELANEKMT2AATMP2RY6MIF
SCHEMBL3419623 0.82 LMNA (0.53) ELANEKMT2AHSD17B10P2RY6CA1
SCHEMBL14690320 0.82 ELANE (0.57) ELANEKMT2AATMLMNAMAPT
SCHEMBL56436 0.82 ELANE (0.69) ELANEKMT2AATMHSD17B10LMNA
Methacrylic Acid SCHEMBL31274994 0.80 HSD17B10 (0.39) ELANEHSD17B10P2RY6CA1CA2
SCHEMBL28536321 0.79 ELANE (0.54) ELANEKMT2AATMHSD17B10LMNA
SCHEMBL7765371 0.78 P2RY6 (0.46) KMT2AHSD17B10P2RY6CA1CA2
SCHEMBL13621641 0.77 ELANE (0.51) ELANEKMT2AATMHSD17B10LMNA
SCHEMBL941110 0.77 ELANE (0.64) ELANEKMT2AATMMAPTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2001059455-A2 IMMOBILIZATION OF BIOACTIVE SPECIES ACSPURT B.V. (NL) 2001-08-16 WO claimed
US-10647784-B2 Resin and surface protective plate or automotive material SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2020-05-12 US disclosed
EP-3327052-B1 RESIN AND SURFACE PROTECTION PLATE OR AUTOMOTIVE MATERIAL SUMITOMO CHEMICAL CO (JP) 2020-03-04 EP disclosed
CN-107849199-B Resin, surface protective plate, or automobile material 住友化学株式会社 2019-12-27 CN disclosed
US-20180215837-A1 RESIN AND SURFACE PROTECTIVE PLATE OR AUTOMOTIVE MATERIAL SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-08-02 US disclosed
EP-3327052-A1 RESIN AND SURFACE PROTECTION PLATE OR AUTOMOTIVE MATERIAL Sumitomo Chemical Company, Ltd. (JP) 2018-05-30 EP disclosed
WO-2001059455-A2 IMMOBILIZATION OF BIOACTIVE SPECIES ACSPURT B.V. (NL) 2001-08-16 WO disclosed
US-4937000-A SILICA-IMMOBILIZED HOMO-AND COPOLYMERS; ADSORBENTS FOR CHROMA TOGRAPHIC SEDARATION BAYER AKTIENGESELLSCHAFT (DE) 1990-06-26 US disclosed
US-4914159-A Optically active (meth)acrylamides, a process for their preparation, and their use for racemate resolution BAYER AKTIENGESELLSCHAFT (DE) 1990-04-03 US disclosed