SCHEMBL20183951

SCHEMBL20183951

C=CC(=O)Oc1cccc(N=C=S)c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MIF P14174 1/20 0.39
THRB P10828 4/20 0.39
P2RY6 Q15077 2/20 0.36
RAD1 O60671 1/20 0.36
CYP3A4 P08684 4/20 0.36
MEN1 O00255 3/20 0.36
KMT2A Q03164 3/20 0.36
ALDH1A1 P00352 3/20 0.36
MAPT P10636 3/20 0.36
ALOX15 P16050 1/20 0.36
EGFR P00533 1/20 0.34
TDP1 Q9NUW8 3/20 0.33
KDM4E B2RXH2 2/20 0.33
USP2 O75604 2/20 0.33
LTA P01374 2/20 0.33
HPGD P15428 2/20 0.33
P2RX3 P56373 2/20 0.33
RAD51 Q06609 2/20 0.33
HSD17B10 Q99714 2/20 0.33
THRA P10827 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL633251 0.86 KMT2A (0.37) THRBCYP3A4MEN1KMT2AALDH1A1
SCHEMBL14689870 0.85 KMT2A (0.41) THRBCYP3A4MEN1KMT2AALDH1A1
SCHEMBL14689871 0.85 KMT2A (0.41) THRBCYP3A4MEN1KMT2AALDH1A1
SCHEMBL20183978 0.82 THRB (0.47) MIFTHRBP2RY6RAD1CYP3A4
SCHEMBL27461707 0.81 MIF (0.41) MIFP2RY6RAD1CYP3A4MEN1
SCHEMBL20183973 0.79 ELANE (0.46) MIFP2RY6RAD1CYP3A4MEN1
SCHEMBL421454 0.78 KMT2A (0.56) THRBCYP3A4MEN1KMT2AALDH1A1
SCHEMBL28520567 0.77 ALDH1A1 (0.39) THRBCYP3A4MEN1KMT2AALDH1A1
SCHEMBL5796149 0.74 MIF (0.44) MIFP2RY6CYP3A4MEN1KMT2A
SCHEMBL28466931 0.74 THRB (0.43) MIFTHRBCYP3A4ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10647784-B2 Resin and surface protective plate or automotive material SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2020-05-12 US disclosed
EP-3327052-B1 RESIN AND SURFACE PROTECTION PLATE OR AUTOMOTIVE MATERIAL SUMITOMO CHEMICAL CO (JP) 2020-03-04 EP disclosed
CN-107849199-B Resin, surface protective plate, or automobile material 住友化学株式会社 2019-12-27 CN disclosed
US-20180215837-A1 RESIN AND SURFACE PROTECTIVE PLATE OR AUTOMOTIVE MATERIAL SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-08-02 US disclosed
EP-3327052-A1 RESIN AND SURFACE PROTECTION PLATE OR AUTOMOTIVE MATERIAL Sumitomo Chemical Company, Ltd. (JP) 2018-05-30 EP disclosed