SCHEMBL20183974

SCHEMBL20183974

C=C(C)C(=O)OCC(COC(=O)C(=C)C)N=C=S

nearest known ligand 0.53

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.53
THRB P10828 1/20 0.38
ALDH1A1 P00352 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20183942 0.84 TSHR (0.56) TSHRTHRBALDH1A1
SCHEMBL1132033 0.84 TSHR (0.55) TSHRTHRBALDH1A1
SCHEMBL14772585 0.77 TSHR (0.61) TSHRTHRBALDH1A1
SCHEMBL9063433 0.76 TSHR (0.50) TSHRTHRBALDH1A1
SCHEMBL1852500 0.76 TSHR (0.50) TSHRTHRBALDH1A1
SCHEMBL19468968 0.75 TSHR (0.53) TSHRTHRBALDH1A1
SCHEMBL2479915 0.73 TSHR (0.47) TSHRTHRBALDH1A1
SCHEMBL20719918 0.73 TSHR (0.47) TSHRTHRBALDH1A1
SCHEMBL13010465 0.73 TSHR (0.55) TSHRTHRBALDH1A1
SCHEMBL7130277 0.73 TSHR (0.55) TSHRTHRBALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10647784-B2 Resin and surface protective plate or automotive material SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2020-05-12 US disclosed
EP-3327052-B1 RESIN AND SURFACE PROTECTION PLATE OR AUTOMOTIVE MATERIAL SUMITOMO CHEMICAL CO (JP) 2020-03-04 EP disclosed
US-20180215837-A1 RESIN AND SURFACE PROTECTIVE PLATE OR AUTOMOTIVE MATERIAL SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-08-02 US disclosed
EP-3327052-A1 RESIN AND SURFACE PROTECTION PLATE OR AUTOMOTIVE MATERIAL Sumitomo Chemical Company, Ltd. (JP) 2018-05-30 EP disclosed