Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5367647 | 0.76 | MAPT (0.31) | MAPT | |
| SCHEMBL10589330 | 0.75 | MAPT (0.38) | KDM4EALDH1A1POLBMAPT | |
| SCHEMBL28168678 | 0.74 | ALDH1A1 (0.38) | ALDH1A1 | |
| SCHEMBL10589396 | 0.73 | MAPT (0.38) | KDM4EALDH1A1POLBMAPT | |
| SCHEMBL7574079 | 0.72 | PIK3CD (0.33) | ALDH1A1 | |
| SCHEMBL346282 | 0.70 | — | — | |
| SCHEMBL29942154 | 0.70 | BACE1 (0.35) | MAPT | |
| SCHEMBL29039578 | 0.67 | ALDH1A1 (0.41) | KDM4EALDH1A1RECQLMAPT | |
| SCHEMBL4708585 | 0.67 | CA2 (0.46) | — | |
| SCHEMBL5355939 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3325466-A1 | SUBSTITUTED CYCLIC ARYL AND HETEROARYL CARBOXYLIC ACID HYDRAZIDES OR SALTS THEREOF AND USE THEREOF TO INCREASE STRESS TOLERANCE IN PLANTS | Bayer CropScience Aktiengesellschaft (DE) | 2018-05-30 | — | — | EP | disclosed |