Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | NQO2 | P16083 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HTR1B | P28222 | 2/20 | 0.40 |
| ▸ | ACP3 | P15309 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.38 |
| ▸ | OGG1 | O15527 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1719111 | 0.98 | CA2 (0.45) | CA2NQO2TDP1ALDH1A1KDM4E | |
| SCHEMBL27458209 | 0.97 | CA2 (0.44) | CA2NQO2TDP1ALDH1A1KDM4E | |
| SCHEMBL10404719 | 0.83 | CA2 (0.45) | CA2NQO2TDP1ALDH1A1KDM4E | |
| SCHEMBL10404597 | 0.83 | ALDH1A1 (0.51) | TDP1ALDH1A1KDM4EHPGDMEN1 | |
| SCHEMBL1549000 | 0.82 | KMT2A (0.56) | CA2TDP1ALDH1A1KDM4EHPGD | |
| SCHEMBL29898474 | 0.81 | ALDH1A1 (0.47) | CA2TDP1ALDH1A1KDM4EHPGD | |
| SCHEMBL9244887 | 0.81 | ALDH1A1 (0.47) | CA2TDP1ALDH1A1KDM4EHPGD | |
| SCHEMBL28811390 | 0.81 | KMT2A (0.54) | CA2TDP1ALDH1A1KDM4EHPGD | |
| SCHEMBL4484229 | 0.80 | TSHR (0.46) | TDP1ALDH1A1KDM4EHPGDMEN1 | |
| SCHEMBL29898466 | 0.80 | ALDH1A1 (0.46) | CA2TDP1ALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3327488-B1 | OPTICAL ARTICLE COMPRISING A DYE RESISTANT TO PHOTO-DEGRADATION | ESSILOR INT (FR) | 2021-01-06 | — | — | EP | disclosed |
| WO-2018095671-A1 | OPTICAL ARTICLE COMPRISING A DYE RESISTANT TO PHOTO-DEGRADATION | ESSILOR INTERNATIONAL (FR) | 2018-05-31 | — | — | WO | disclosed |
| EP-3327488-A1 | OPTICAL ARTICLE COMPRISING A DYE RESISTANT TO PHOTO-DEGRADATION | Essilor International (FR) | 2018-05-30 | — | — | EP | disclosed |