Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20184289 | 0.86 | P2RX7 (0.50) | P2RX7CYP2C8 | |
| SCHEMBL18860806 | 0.80 | P2RX7 (0.54) | P2RX7 | |
| SCHEMBL28670732 | 0.79 | P2RX7 (0.65) | P2RX7CYP2C8 | |
| SCHEMBL19524407 | 0.77 | P2RX7 (0.56) | P2RX7 | |
| SCHEMBL20184278 | 0.77 | P2RX7 (0.47) | P2RX7 | |
| SCHEMBL20184275 | 0.77 | P2RX7 (0.53) | P2RX7 | |
| SCHEMBL20184305 | 0.76 | P2RX7 (0.37) | P2RX7 | |
| SCHEMBL18860816 | 0.76 | P2RX7 (0.51) | P2RX7 | |
| SCHEMBL16036244 | 0.74 | P2RX7 (0.59) | P2RX7CYP2C8 | |
| SCHEMBL18880941 | 0.72 | P2RX7 (0.53) | P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970267-B3 | P2X7 MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2018-05-30 | — | — | EP | claimed |