Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20184288 | 0.86 | P2RX7 (0.54) | P2RX7 | |
| SCHEMBL20184308 | 0.84 | P2RX7 (0.52) | P2RX7 | |
| SCHEMBL20184289 | 0.78 | P2RX7 (0.50) | P2RX7 | |
| SCHEMBL17244877 | 0.74 | P2RX7 (0.80) | P2RX7 | |
| SCHEMBL16089684 | 0.74 | P2RX7 (0.80) | P2RX7 | |
| SCHEMBL16036449 | 0.72 | P2RX7 (1.00) | P2RX7 | |
| SCHEMBL16036349 | 0.72 | P2RX7 (1.00) | P2RX7 | |
| SCHEMBL20184305 | 0.71 | P2RX7 (0.37) | P2RX7 | |
| SCHEMBL18880941 | 0.70 | P2RX7 (0.53) | P2RX7 | |
| SCHEMBL19524407 | 0.70 | P2RX7 (0.56) | P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970267-B3 | P2X7 MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2018-05-30 | — | — | EP | claimed |