Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 20/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20184308 | 0.86 | P2RX7 (0.52) | P2RX7 | |
| SCHEMBL20184300 | 0.86 | P2RX7 (0.56) | P2RX7 | |
| SCHEMBL20184289 | 0.81 | P2RX7 (0.50) | P2RX7 | |
| SCHEMBL20184305 | 0.74 | P2RX7 (0.37) | P2RX7 | |
| SCHEMBL18880941 | 0.73 | P2RX7 (0.53) | P2RX7 | |
| SCHEMBL20184286 | 0.73 | P2RX7 (0.56) | P2RX7 | |
| SCHEMBL19524407 | 0.73 | P2RX7 (0.56) | P2RX7 | |
| SCHEMBL20184275 | 0.72 | P2RX7 (0.53) | P2RX7 | |
| SCHEMBL16035705 | 0.72 | P2RX7 (0.69) | P2RX7 | |
| SCHEMBL29689839 | 0.71 | P2RX7 (0.57) | P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970267-B3 | P2X7 MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2018-05-30 | — | — | EP | claimed |