Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 6/20 | 0.58 |
| ▸ | PLG | P00747 | 5/20 | 0.58 |
| ▸ | PLAU | P00749 | 5/20 | 0.58 |
| ▸ | KLKB1 | P03952 | 5/20 | 0.58 |
| ▸ | F2 | P00734 | 5/20 | 0.58 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.58 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 5/20 | 0.58 |
| ▸ | RAB9A | P51151 | 5/20 | 0.58 |
| ▸ | TP53 | P04637 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | PLAT | P00750 | 4/20 | 0.56 |
| ▸ | KLK1 | P06870 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.54 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.54 |
| ▸ | RELA | Q04206 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8716123 | 0.85 | ITGB3 (0.55) | PRSS1PLGPLAUKLKB1F2 | |
| SCHEMBL8715620 | 0.80 | PLAU (0.47) | PRSS1PLGPLAUKLKB1F2 | |
| SCHEMBL8716521 | 0.79 | PRMT1 (0.59) | PLAUF2ITGB3ITGA2BPRMT1 | |
| SCHEMBL8718459 | 0.78 | ITGB3 (0.57) | PRSS1PLGPLAUKLKB1F2 | |
| Hydrochloric Acid SCHEMBL8713031 | 0.78 | PRMT1 (0.58) | PLAUF2ITGB3ITGA2BPRMT1 | |
| SCHEMBL8904666 | 0.77 | ITGB3 (0.62) | PRSS1PLGPLAUKLKB1F2 | |
| SCHEMBL8904811 | 0.75 | ITGB3 (0.60) | PRSS1PLGPLAUKLKB1F2 | |
| SCHEMBL8717795 | 0.75 | F2 (0.57) | PRSS1PLGPLAUKLKB1F2 | |
| SCHEMBL8718457 | 0.75 | PLG (0.55) | PRSS1PLGPLAUKLKB1F2 | |
| SCHEMBL8718116 | 0.75 | F2 (0.52) | PRSS1PLGPLAUKLKB1F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1945209-B1 | BROAD SPECTRUM ANTIBACTERIAL COMPOUNDS | US GOV AS REPRESENTED BY THE SECRETARY OF THE UNITED STATES ARMY AND THE U S ARMY MEDICAL RESEARCH (US) | 2018-05-30 | — | — | EP | disclosed |