Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 9/20 | 0.62 |
| ▸ | ITGA2B | P08514 | 9/20 | 0.62 |
| ▸ | F2 | P00734 | 7/20 | 0.53 |
| ▸ | PLG | P00747 | 5/20 | 0.53 |
| ▸ | PLAU | P00749 | 5/20 | 0.53 |
| ▸ | KLKB1 | P03952 | 5/20 | 0.53 |
| ▸ | PRSS1 | P07477 | 5/20 | 0.53 |
| ▸ | PLAT | P00750 | 4/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.48 |
| ▸ | KLK1 | P06870 | 1/20 | 0.48 |
| ▸ | F10 | P00742 | 1/20 | 0.48 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.47 |
| ▸ | ITGAV | P06756 | 1/20 | 0.47 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8718116 | 0.88 | F2 (0.52) | ITGB3ITGA2BF2PLGPLAU | |
| SCHEMBL8718459 | 0.85 | ITGB3 (0.57) | ITGB3ITGA2BF2PLGPLAU | |
| SCHEMBL8904811 | 0.85 | ITGB3 (0.60) | ITGB3ITGA2BF2PLGPLAU | |
| SCHEMBL8717795 | 0.83 | F2 (0.57) | ITGB3ITGA2BF2PLGPLAU | |
| SCHEMBL8903453 | 0.81 | NPC1 (0.48) | ITGB3ITGA2BF2PLGPLAU | |
| SCHEMBL8904679 | 0.80 | PLAU (0.50) | ITGB3ITGA2BF2PLGPLAU | |
| SCHEMBL8716062 | 0.79 | F2 (0.51) | ITGB3ITGA2BF2PLGPLAU | |
| SCHEMBL8904649 | 0.79 | ITGB3 (0.53) | ITGB3ITGA2BF2PLGPLAU | |
| SCHEMBL7371861 | 0.79 | ITGB3 (0.69) | ITGB3ITGA2BF2PLGPLAU | |
| SCHEMBL8718457 | 0.78 | PLG (0.55) | ITGB3ITGA2BF2PLGPLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5635527-A | ANTAGONIST OF PLATELET MEMBRANE GLYCOPROTEIN; TREATMENT OF THROMBOTIC DISEASES | THE GREEN CROSS CORPORATION (JP) | 1997-06-03 | — | — | US | disclosed |
| EP-0712844-A1 | NOVEL FUSED-RING CARBOXYLIC ACID COMPOUND OR SALT THEREOF, AND MEDICINAL USE THEREOF | THE GREEN CROSS CORPORATION (JP) | 1996-05-22 | — | — | EP | disclosed |