SCHEMBL20184760

SCHEMBL20184760

c1cc(-c2cc3cc(C4=NCCN4)ccc3s2)ccc1C1=NCCN1

nearest known ligand 0.79

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
PRMT1 Q99873 1/20 0.64
NISCH Q9Y2I1 10/20 0.55
LMNA P02545 1/20 0.47
RECQL P46063 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12348379 0.88 NISCH (0.55) PRMT1NISCHLMNARECQL
SCHEMBL8229712 0.79 PRMT1 (1.00) PRMT1NISCH
SCHEMBL13135587 0.77 NISCH (0.86) PRMT1NISCHLMNARECQL
SCHEMBL548346 0.76 NISCH (0.54) PRMT1NISCH
Hydrochloric Acid SCHEMBL5562588 0.76 NISCH (0.83) PRMT1NISCHLMNARECQL
Hydrochloric Acid SCHEMBL7050789 0.75 LMNA (0.53) PRMT1NISCHLMNARECQL
SCHEMBL5476725 0.75 NISCH (0.79) NISCHLMNARECQL
SCHEMBL562867 0.74 NISCH (0.53) NISCHLMNA
SCHEMBL9189709 0.71 NISCH (0.85) NISCH
Benazoline SCHEMBL9575180 0.71 NISCH (1.00) PRMT1NISCH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1945209-B1 BROAD SPECTRUM ANTIBACTERIAL COMPOUNDS US GOV AS REPRESENTED BY THE SECRETARY OF THE UNITED STATES ARMY AND THE U S ARMY MEDICAL RESEARCH (US) 2018-05-30 EP disclosed