Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 1.00 |
| ▸ | MEN1 | O00255 | 4/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 4/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 1.00 |
| ▸ | ATM | Q13315 | 2/20 | 1.00 |
| ▸ | CACNA1B | Q00975 | 1/20 | 1.00 |
| ▸ | APBA1 | Q02410 | 1/20 | 1.00 |
| ▸ | MCL1 | Q07820 | 1/20 | 1.00 |
| ▸ | NPC1 | O15118 | 3/20 | 0.65 |
| ▸ | RAB9A | P51151 | 3/20 | 0.65 |
| ▸ | FABP6 | P51161 | 1/20 | 0.57 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.52 |
| ▸ | MMP2 | P08253 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | ADAMTS5 | Q9UNA0 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | METAP1 | P53582 | 2/20 | 0.44 |
| ▸ | METAP2 | P50579 | 1/20 | 0.44 |
| ▸ | CBFB | Q13951 | 1/20 | 0.44 |
| ▸ | AMY1A | P0DUB6 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20184767 | 1.00 | MAPT (1.00) | MAPTMEN1KMT2AKDM4EATM | |
| SCHEMBL6836889 | 0.87 | KDM4E (0.75) | MAPTMEN1KMT2AKDM4EATM | |
| SCHEMBL6836616 | 0.87 | KDM4E (0.75) | MAPTMEN1KMT2AKDM4EATM | |
| SCHEMBL13508624 | 0.85 | MAPT (0.73) | MAPTMEN1KMT2AKDM4EATM | |
| SCHEMBL22656695 | 0.84 | ATM (0.72) | MAPTMEN1KMT2AKDM4EATM | |
| SCHEMBL22075580 | 0.84 | ATM (0.72) | MAPTMEN1KMT2AKDM4EATM | |
| SCHEMBL29017313 | 0.81 | ATM (0.68) | MAPTMEN1KMT2AKDM4EATM | |
| SCHEMBL2458503 | 0.81 | RAB9A (1.00) | MAPTMEN1KMT2AKDM4EATM | |
| SCHEMBL2458502 | 0.81 | RAB9A (1.00) | MAPTMEN1KMT2AKDM4EATM | |
| SCHEMBL29770338 | 0.76 | MAPT (0.59) | MAPTMEN1KMT2AKDM4EATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1945209-B1 | BROAD SPECTRUM ANTIBACTERIAL COMPOUNDS | US GOV AS REPRESENTED BY THE SECRETARY OF THE UNITED STATES ARMY AND THE U S ARMY MEDICAL RESEARCH (US) | 2018-05-30 | — | — | EP | disclosed |