Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | FABP5 | Q01469 | 3/20 | 0.43 |
| ▸ | FABP7 | O15540 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27960451 | 1.00 | KMT2A (0.47) | KMT2AEPHX2FABP5FABP7CA1 | |
| SCHEMBL30341743 | 0.89 | KMT2A (0.49) | KMT2AEPHX2FABP5FABP7CA1 | |
| SCHEMBL2817872 | 0.85 | KMT2A (0.42) | KMT2AEPHX2FABP5FABP7CA1 | |
| SCHEMBL28857903 | 0.84 | KMT2A (0.50) | KMT2AEPHX2FABP5FABP7CA1 | |
| SCHEMBL8037760 | 0.82 | KMT2A (0.42) | KMT2AEPHX2FABP5FABP7CA1 | |
| SCHEMBL15058849 | 0.82 | KMT2A (0.55) | KMT2AEPHX2FABP5FABP7CA1 | |
| SCHEMBL29823519 | 0.82 | KMT2A (0.48) | KMT2AEPHX2FABP5FABP7CA1 | |
| SCHEMBL17760519 | 0.82 | KMT2A (0.48) | KMT2AEPHX2FABP5FABP7CA1 | |
| SCHEMBL19280973 | 0.82 | KMT2A (0.45) | KMT2AEPHX2FABP5FABP7CASP3 | |
| SCHEMBL23296943 | 0.81 | KMT2A (0.44) | KMT2AEPHX2FABP5FABP7CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3327027-A1 | CYTOTOXIC PEPTIDES AND ANTIBODY DRUG CONJUGATES THEREOF | Pfizer Inc (US) | 2018-05-30 | — | — | EP | disclosed |