SCHEMBL19280973

SCHEMBL19280973

CN[C@H](C(=O)OC(=O)OCC1c2ccccc2-c2ccccc21)C(C)C

nearest known ligand 0.46

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.45
CASP3 P42574 4/20 0.45
EPHX2 P34913 1/20 0.43
FABP5 Q01469 3/20 0.41
FABP7 O15540 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9234192 0.89 KMT2A (0.43) KMT2ACASP3EPHX2FABP5FABP7
SCHEMBL4413972 0.82 KMT2A (0.43) KMT2ACASP3EPHX2FABP5FABP7
SCHEMBL27960451 0.82 KMT2A (0.47) KMT2ACASP3EPHX2FABP5FABP7
SCHEMBL20184843 0.82 KMT2A (0.47) KMT2ACASP3EPHX2FABP5FABP7
SCHEMBL30341743 0.81 KMT2A (0.49) KMT2ACASP3EPHX2FABP5FABP7
SCHEMBL15119354 0.80 KMT2A (0.60) KMT2ACASP3EPHX2FABP5FABP7
SCHEMBL15058849 0.80 KMT2A (0.55) KMT2ACASP3EPHX2FABP5FABP7
SCHEMBL19517972 0.79 KMT2A (0.45) KMT2ACASP3EPHX2FABP5FABP7
SCHEMBL23296943 0.79 KMT2A (0.44) KMT2ACASP3EPHX2FABP5FABP7
SCHEMBL28857903 0.79 KMT2A (0.50) KMT2ACASP3EPHX2FABP5FABP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190209704-A1 NOVEL ANTIBODY-DRUG CONJUGATES AND RELATED COMPOUNDS, COMPOSITIONS AND METHODS OF USE SENSEI BIOTHERAPEUTICS, INC. 2019-07-11 US disclosed
EP-3209334-A2 NOVEL ANTIBODY-DRUG CONJUGATES AND RELATED COMPOUNDS, COMPOSITIONS, AND METHODS OF USE Igenica Biotherapeutics, Inc. (US) 2017-08-30 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190209704-A1 NOVEL ANTIBODY-DRUG CONJUGATES AND RELATED COMPOUNDS, COMPOSITIONS AND METHODS OF USE CYTH3, CD47, FCGRT KMT2A 2145/4885CASP3 572/4885EPHX2 741/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.