Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | FABP5 | Q01469 | 3/20 | 0.39 |
| ▸ | FABP7 | O15540 | 2/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | MDM4 | O15151 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2817872 | 0.88 | KMT2A (0.42) | KMT2AFABP5FABP7EPHX2MDM4 | |
| SCHEMBL20184843 | 0.82 | KMT2A (0.47) | KMT2AFABP5FABP7EPHX2CASP3 | |
| SCHEMBL27960451 | 0.82 | KMT2A (0.47) | KMT2AFABP5FABP7EPHX2CASP3 | |
| SCHEMBL8035578 | 0.80 | KMT2A (0.41) | KMT2AFABP5FABP7EPHX2MDM4 | |
| SCHEMBL30341743 | 0.80 | KMT2A (0.49) | KMT2AFABP5FABP7EPHX2CASP3 | |
| SCHEMBL1738680 | 0.76 | MDM4 (0.49) | KMT2AEPHX2MDM4TP53CASP3 | |
| SCHEMBL30785203 | 0.76 | MDM4 (0.49) | KMT2AEPHX2MDM4TP53CASP3 | |
| SCHEMBL28341996 | 0.76 | MDM4 (0.49) | KMT2AEPHX2MDM4TP53CASP3 | |
| SCHEMBL8037756 | 0.76 | MDM4 (0.49) | KMT2AEPHX2MDM4TP53CASP3 | |
| SCHEMBL3439365 | 0.75 | CASP3 (0.48) | KMT2AEPHX2MDM4TP53CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0989136-A1 | PEPTIDES HAVING CYCLIC STRUCTURES AND EXERTING P53 PROTEIN ACTIVTY-RESTORING EFFECT ON P53 PROTEIN MUTANTS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2000-03-29 | — | — | EP | disclosed |