Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CRHR1 | P34998 | 3/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | IP6K1 | Q92551 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18208204 | 1.00 | L3MBTL1 (0.40) | L3MBTL1CRHR1CRHR2CNR1CNR2 | |
| SCHEMBL18216524 | 0.97 | CRHR1 (0.39) | L3MBTL1CRHR1CRHR2CNR1CNR2 | |
| SCHEMBL18216270 | 0.92 | HPGD (0.41) | L3MBTL1CRHR1CRHR2ALDH1A1HPGD | |
| SCHEMBL20184995 | 0.92 | HPGD (0.41) | L3MBTL1CRHR1CRHR2ALDH1A1HPGD | |
| SCHEMBL20205205 | 0.92 | HPGD (0.41) | L3MBTL1CRHR1CRHR2ALDH1A1HPGD | |
| SCHEMBL20184954 | 0.91 | KMT2A (0.43) | L3MBTL1CRHR1CRHR2CNR1CNR2 | |
| SCHEMBL18208486 | 0.91 | KMT2A (0.43) | L3MBTL1CRHR1CRHR2CNR1CNR2 | |
| SCHEMBL18208662 | 0.91 | L3MBTL1 (0.39) | L3MBTL1CRHR1CRHR2CNR1CNR2 | |
| SCHEMBL20184972 | 0.91 | L3MBTL1 (0.39) | L3MBTL1CRHR1CRHR2CNR1CNR2 | |
| SCHEMBL20205113 | 0.90 | KMT2A (0.41) | L3MBTL1CRHR1CRHR2ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180148418-A1 | AMIDO-SUBSTITUTED CYCLOHEXANE DERIVATIVES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2018-05-31 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180148418-A1 | AMIDO-SUBSTITUTED CYCLOHEXANE DERIVATIVES | C1R, C9, C1S | L3MBTL1 2341/4885CRHR1 1606/4885CRHR2 2704/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.