SCHEMBL201853

SCHEMBL201853

BrCc1cccc(-n2cccc2)c1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AOC2 O75106 3/20 0.51
MAPT P10636 2/20 0.50
ALDH1A1 P00352 2/20 0.41
TRPA1 O75762 1/20 0.41
TSHR P16473 1/20 0.41
VHL P40337 1/20 0.41
ELOC Q15369 1/20 0.41
ELOB Q15370 1/20 0.41
FFAR4 Q5NUL3 1/20 0.40
POLB P06746 2/20 0.36
CASP6 P55212 2/20 0.36
NSD2 O96028 1/20 0.36
GRK2 P25098 1/20 0.36
CTDSP1 Q9GZU7 1/20 0.36
NR1H3 Q13133 1/20 0.36
MRGPRX4 Q96LA9 1/20 0.36
GAA P10253 1/20 0.35
L3MBTL1 Q9Y468 2/20 0.35
KDM4E B2RXH2 1/20 0.34
HPGD P15428 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27653525 0.84 AOC2 (0.49) AOC2MAPTALDH1A1VHLELOC
SCHEMBL327268 0.79 MGLL (0.55) AOC2MAPTVHLELOCELOB
SCHEMBL20780668 0.79 AOC2 (0.51) AOC2MAPTALDH1A1VHLELOC
SCHEMBL109402 0.79 AOC2 (0.56) AOC2MAPTALDH1A1VHLELOC
SCHEMBL1508370 0.79 VHL (0.61) AOC2MAPTALDH1A1TSHRVHL
SCHEMBL4705522 0.79 AOC2 (0.51) AOC2MAPTALDH1A1VHLELOC
SCHEMBL16417013 0.79 AOC2 (0.47) AOC2MAPTALDH1A1TSHRVHL
SCHEMBL20319187 0.77 MAPT (0.68) AOC2MAPTALDH1A1VHLELOC
SCHEMBL321086 0.76 AOC2 (0.49) AOC2MAPTVHLELOCELOB
SCHEMBL21368820 0.76 AOC2 (0.53) AOC2MAPTALDH1A1VHLELOC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 101 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250179008-A1 ANTIBACTERIAL AGENTS TAXIS PHARMACEUTICALS, INC. (US) 2025-06-05 US disclosed
CN-114502677-B Black particles, black paint, coating film, and black matrix for color filter 积水化学工业株式会社 2023-11-14 CN disclosed
CN-114502677-A Black particles, black paint, coating film and black matrix for color filter 积水化学工业株式会社 2022-05-13 CN disclosed
CN-102079743-B Dipeptidyl peptidase inhibitors 武田药品工业株式会社 2020-08-25 CN disclosed
CN-102134229-B Dipeptidyl peptidase inhibitors 武田药品工业株式会社 2020-08-04 CN disclosed
CN-102134231-B Dipeptidyl peptidase inhibitors 武田药品工业株式会社 2020-08-04 CN disclosed
CN-106232584-B As 6 inhibitor of histone deacetylase new compound and include its pharmaceutical composition 株式会社钟根堂 2019-06-28 CN disclosed
CN-102134230-B Dipeptidyl peptidase inhibitors 武田药品工业株式会社 2019-06-28 CN disclosed
US-10287255-B2 Compounds as histone deacetylase 6 inhibitors and pharmaceutical compositions comprising the same CHONG KUN DANG PHARMACEUTICAL CORP. (KR) 2019-05-14 US disclosed
EP-3116859-B1 NOVEL COMPOUNDS AS HISTONE DEACETYLASE 6 INHIBITORS AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME CHONG KUN DANG PHARMACEUTICAL CORP (KR) 2018-08-01 EP disclosed
WO-2007139813-A1 IMIDAZOAZEPHINONE COMPOUNDS EISAI R&D MANAGEMENT CO., LTD (JP) 2007-12-06 WO disclosed
US-20070244148-A1 Imidazo 4,5-C Pyridine Compounds and Methods of Antiviral Treatment KATHOLIEKE UNIVERSITEIT LEUVEN (BE) 2007-10-18 US disclosed
US-20070244148-A1 Imidazo 4,5-C Pyridine Compounds and Methods of Antiviral Treatment KATHOLIEKE UNIVERSITEIT LEUVEN (BE) 2007-10-18 US disclosed
WO-2007107758-A1 ANTIBACTERIAL AGENTS PROLYSIS LTD (GB) 2007-09-27 WO disclosed
EP-1836163-A2 PYRROLIDINE DERIVATIVES FOR THE TREATMENT OF A DISEASE DEPENDING ON THE ACTIVITY OF RENIN Novartis AG (CH) 2007-09-26 EP disclosed
WO-2007035629-A2 PROCESS FOR THE PREPARATION OF PYRIMIDINEDIONE DERIVATIVES TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2007-03-29 WO disclosed
WO-2006066896-A2 PYRROLIDINE DERIVATIVES FOR THE TREATMENT OF A DISEASE DEPENDING ON THE ACTIVITY OF RENIN NOVARTIS AG (CH) 2006-06-29 WO disclosed
US-20050261271-A1 Dipeptidyl peptidase inhibitors TAKEDA SAN DIEGO, INC. 2005-11-24 US disclosed
EP-1586571-A1 Dipeptidyl peptidase inhibitors Takeda San Diego, Inc. (US) 2005-10-19 EP disclosed
WO-2005095381-A1 DIPEPTIDYL PEPTIDASE INHIBITORS TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2005-10-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10287255-B2 Compounds as histone deacetylase 6 inhibitors and pharmaceutical compositions comprising the same HDAC6, HDAC1, HDAC11 AOC2 3293/4885MAPT 369/4885ALDH1A1 1133/4885
US-20070244148-A1 Imidazo 4,5-C Pyridine Compounds and Methods of Antiviral Treatment ZC3HAV1, TPMT, DPP4 AOC2 3678/4885MAPT 4159/4885ALDH1A1 1580/4885
US-20050261271-A1 Dipeptidyl peptidase inhibitors DPP4, DPP3, DPP9 AOC2 2730/4885MAPT 4578/4885ALDH1A1 1477/4885
US-20250179008-A1 ANTIBACTERIAL AGENTS ALK, ROS1, NOX1 AOC2 44/4885MAPT 4784/4885ALDH1A1 800/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.