Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27637713 | 0.84 | ALDH1A1 (0.34) | ALDH1A1ALOX15LMNAHSD17B10 | |
| SCHEMBL28754649 | 0.84 | ALDH1A1 (0.34) | ALDH1A1ALOX15LMNAHSD17B10 | |
| SCHEMBL27637712 | 0.84 | ALDH1A1 (0.34) | ALDH1A1ALOX15LMNAHSD17B10 | |
| SCHEMBL27618527 | 0.75 | GAA (0.38) | ALDH1A1TSHRALOX15HSD17B10 | |
| SCHEMBL4693468 | 0.72 | ALDH1A1 (0.36) | ALDH1A1TSHRALOX15LMNAHSD17B10 | |
| SCHEMBL4690823 | 0.71 | CHRM1 (0.34) | ALDH1A1TSHRALOX15LMNAHSD17B10 | |
| SCHEMBL4689856 | 0.71 | ALDH1A1 (0.35) | ALDH1A1ALOX15LMNAHSD17B10 | |
| SCHEMBL15802621 | 0.71 | ALDH1A1 (0.35) | ALDH1A1ALOX15LMNAHSD17B10 | |
| SCHEMBL6616081 | 0.69 | ESR2 (0.44) | ALDH1A1HSD17B10 | |
| SCHEMBL28571854 | 0.69 | PRKCA (0.32) | NLRP3ALDH1A1ALOX15LMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10618898-B2 | Hydroxyl purine compounds and use thereof | Guangdong Raynovent Biotech Co., Ltd. (CN) | 2020-04-14 | — | — | US | disclosed |
| CN-107614501-B | Hydroxyl purine compound and application thereof | 广东众生睿创生物科技有限公司 | 2020-01-14 | — | — | CN | disclosed |
| US-20180148451-A1 | HYDROXYL PURINE COMPOUNDS AND USE THEREOF | Guangdong Raynovent Biotech Co., Ltd. (CN) | 2018-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180148451-A1 | HYDROXYL PURINE COMPOUNDS AND USE THEREOF | PNP, PDE7A, PDE2A | NLRP3 305/4885ALDH1A1 380/4885TSHR 3261/4885 |
| US-10618898-B2 | Hydroxyl purine compounds and use thereof | PNP, PDE7A, PDE2A | NLRP3 305/4885ALDH1A1 380/4885TSHR 3261/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.