Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 8/20 | 0.53 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MC4R | P32245 | 1/20 | 0.34 |
| ▸ | MC5R | P33032 | 1/20 | 0.34 |
| ▸ | MC3R | P41968 | 1/20 | 0.34 |
| ▸ | MC1R | Q01726 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20185673 | 1.00 | SIGMAR1 (0.53) | SIGMAR1EPHX1ALOX15TSHRMAPK14 | |
| SCHEMBL18230710 | 0.86 | SIGMAR1 (0.50) | SIGMAR1EPHX1CHRM5CHRM3MC4R | |
| SCHEMBL18230709 | 0.86 | SIGMAR1 (0.50) | SIGMAR1EPHX1CHRM5CHRM3MC4R | |
| SCHEMBL7623949 | 0.82 | SIGMAR1 (0.71) | SIGMAR1EPHX1CHRM5CHRM3EPHX2 | |
| SCHEMBL7623945 | 0.82 | SIGMAR1 (0.71) | SIGMAR1EPHX1CHRM5CHRM3EPHX2 | |
| SCHEMBL17187436 | 0.82 | SIGMAR1 (0.53) | SIGMAR1EPHX1MAPK14KDM4E | |
| SCHEMBL17187438 | 0.82 | SIGMAR1 (0.53) | SIGMAR1EPHX1MAPK14KDM4E | |
| Piperazine SCHEMBL28204588 | 0.81 | SIGMAR1 (0.54) | SIGMAR1EPHX1CHRM5CHRM3KDM4E | |
| SCHEMBL18740827 | 0.77 | SIGMAR1 (0.68) | SIGMAR1EPHX1KDM4E | |
| SCHEMBL17187490 | 0.76 | SIGMAR1 (0.49) | SIGMAR1EPHX1MAPK14KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113265053-A | Catalyst having polysiloxane structural units for curable compositions | SIKA技术股份公司 | 2021-08-17 | — | — | CN | disclosed |
| CN-108473815-B | Catalyst having polysiloxane structural units for curable compositions | SIKA技术股份公司 | 2021-05-28 | — | — | CN | disclosed |
| EP-3795649-A2 | CATALYST WITH POLYSILOXANE STRUCTURE UNIT FOR CURABLE COMPOSITIONS | SIKA TECHNOLOGY AG (CH) | 2021-03-24 | — | — | EP | disclosed |
| EP-3294803-B1 | GUANIDINE GROUP CONTAINING CATALYST | SIKA TECH AG (CH) | 2020-12-09 | — | — | EP | disclosed |
| US-10836868-B2 | Catalyst having a polysiloxane structural unit for hardenable compositions | SIKA TECHNOLOGY AG (CH) | 2020-11-17 | — | — | US | disclosed |
| CN-107735438-B | Guanidino-containing catalysts | SIKA技术股份公司 | 2020-06-09 | — | — | CN | disclosed |
| US-10414875-B2 | Catalyst containing guanidine groups | SIKA TECHNOLOGY AG (CH) | 2019-09-17 | — | — | US | disclosed |
| US-20180327549-A1 | CATALYST HAVING A POLYSILOXANE STRUCTURAL UNIT FOR HARDENABLE COMPOSITIONS | SIKA TECHNOLOGY AG (CH) | 2018-11-15 | — | — | US | disclosed |
| CN-108473815-A | Catalyst having polysiloxane structural units for curable compositions | SIKA技术股份公司 | 2018-08-31 | — | — | CN | disclosed |
| US-20180148545-A1 | CATALYST CONTAINING GUANIDINE GROUPS | SIKA TECHNOLOGY AG (CH) | 2018-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10414875-B2 | Catalyst containing guanidine groups | GMPS, GMNN, RNMT | SIGMAR1 764/4885EPHX1 2367/4885ALOX15 3543/4885 |
| US-20180148545-A1 | CATALYST CONTAINING GUANIDINE GROUPS | GMPS, RNMT, GMNN | SIGMAR1 1068/4885EPHX1 2252/4885ALOX15 3732/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.