Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PFKFB3 | Q16875 | 12/20 | 0.52 |
| ▸ | IRAK4 | Q9NWZ3 | 4/20 | 0.47 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.47 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.43 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.43 |
| ▸ | PI4KA | P42356 | 1/20 | 0.43 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.43 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18228215 | 1.00 | PFKFB3 (0.52) | PFKFB3IRAK4IRAK1DYRK1APIK3CD | |
| SCHEMBL31456988 | 1.00 | PFKFB3 (0.52) | PFKFB3IRAK4IRAK1DYRK1APIK3CD | |
| SCHEMBL30952714 | 0.88 | PFKFB3 (0.49) | PFKFB3IRAK4IRAK1DYRK1A | |
| SCHEMBL14870415 | 0.87 | PFKFB3 (0.57) | PFKFB3IRAK4IRAK1DYRK1A | |
| Hydrochloric Acid SCHEMBL30806069 | 0.81 | PFKFB3 (0.41) | PFKFB3PIK3CDPIK3CAPIK3CBPI4KA | |
| SCHEMBL19604964 | 0.80 | GPR55 (0.48) | PFKFB3DYRK1APIK3CDPIK3CAPIK3CB | |
| SCHEMBL16089005 | 0.80 | GPR55 (0.48) | PFKFB3DYRK1APIK3CDPIK3CAPIK3CB | |
| SCHEMBL12453539 | 0.80 | GPR55 (0.48) | PFKFB3DYRK1APIK3CDPIK3CAPIK3CB | |
| SCHEMBL18239336 | 0.79 | MKNK1 (0.50) | PFKFB3DYRK1APIK3CDPIK3CAPIK3CB | |
| SCHEMBL18228546 | 0.79 | MKNK1 (0.50) | PFKFB3DYRK1APIK3CDPIK3CAPIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180148429-A1 | SUBSTITUTED QUINOXALINE DERIVATIVES | SELVITA S.A. (PL) | 2018-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180148429-A1 | SUBSTITUTED QUINOXALINE DERIVATIVES | BRCA1, NQO2, NQO1 | PFKFB3 1161/4885IRAK4 1577/4885IRAK1 1912/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.