SCHEMBL20187

SCHEMBL20187

[CH2]c1ccccc1[N+](=O)[O-]

nearest known ligand 0.54

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.54
TDP1 Q9NUW8 5/20 0.52
ALDH1A1 P00352 8/20 0.50
KMT2A Q03164 2/20 0.50
MEN1 O00255 1/20 0.50
GPR35 Q9HC97 1/20 0.50
TSHR P16473 3/20 0.48
NPC1 O15118 1/20 0.47
RECQL P46063 1/20 0.47
RAB9A P51151 1/20 0.47
MAPK1 P28482 1/20 0.45
CASP7 P55210 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
LMNA P02545 1/20 0.44
HPGD P15428 1/20 0.44
PLAU P00749 1/20 0.44
PTPRC P08575 1/20 0.44
S100A4 P26447 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromide SCHEMBL28070585 0.98 HSD17B10 (0.52) HSD17B10TDP1ALDH1A1KMT2AMEN1
SCHEMBL8347885 0.84 HSD17B10 (0.46) HSD17B10TDP1ALDH1A1KMT2AMEN1
Ethylene SCHEMBL27275849 0.81 HSD17B10 (0.61) HSD17B10TDP1ALDH1A1KMT2AMEN1
Formaldehyde SCHEMBL10823877 0.81 HSD17B10 (0.61) HSD17B10TDP1ALDH1A1KMT2AMEN1
SCHEMBL29577518 0.81 HSD17B10 (0.67) HSD17B10TDP1ALDH1A1KMT2AMEN1
SCHEMBL16355165 0.81 HSD17B10 (0.67) HSD17B10TDP1ALDH1A1KMT2AMEN1
SCHEMBL22566 0.81 HSD17B10 (0.67) HSD17B10TDP1ALDH1A1KMT2AMEN1
SCHEMBL566064 0.79 TSHR (0.59) HSD17B10TDP1ALDH1A1KMT2AMEN1
Ethylene SCHEMBL27836925 0.79 HSD17B10 (0.58) HSD17B10TDP1ALDH1A1KMT2AMEN1
Fluoride SCHEMBL11797732 0.78 HSD17B10 (0.64) HSD17B10TDP1ALDH1A1KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 38939 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4400166-A2 METHODS FOR IMPLANTING AND REVERSING STIMULI-RESPONSIVE IMPLANTS Contraline, Inc. (US) 2024-07-17 EP claimed
EP-4399212-A1 SUBSTITUTED 2,3-DIHYDRO[1,3]THIAZOLO[4,5-B]PYRIDINES, SALTS THEREOF AND THEIR USE AS HERBICIDALLY ACTIVE SUBSTANCES Bayer Aktiengesellschaft (DE) 2024-07-17 EP claimed
CN-118325715-A Nucleic acid detection system and nucleic acid detection method 南方医科大学南方医院 2024-07-12 CN claimed
CN-118339173-A Method for preparing polynucleotide ATD生物有限公司 2024-07-12 CN claimed
EP-4396338-A1 ACTIVATABLE DNA POLYMERASE Ludwig-Maximilians-Universität München (DE) 2024-07-10 EP claimed
EP-3681546-B1 AN AGENT FOR BIOLOGICAL DAMAGE REPAIR OR HEMOSTASIS AND METHOD THEREOF HAINING ZHULUOJI BIOTECHNOLOGY CO LTD (CN) 2024-07-10 EP claimed
CN-118318020-A Adhesive and/or cohesive agent 日东电工株式会社 2024-07-09 CN claimed
WO-2024142909-A1 COMPOUND, POLYMER COMPOUND, PHOTOSENSITIVE SURFACE TREATMENT AGENT, LAMINATE, SUBSTRATE FOR PATTERN FORMATION, TRANSISTOR, PATTERN FORMATION METHOD, AND TRANSISTOR MANUFACTURING METHOD 株式会社ニコン 2024-07-04 WO claimed
US-12018325-B2 3′-O-modified nucleotide analogues with different cleavable linkers for attaching fluorescent labels to the base for DNA sequencing by synthesis THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 2024-06-25 US claimed
US-20240200059-A1 PHOTOCLEAVABLE GUIDE RNAS AND METHODS OF USE THEREOF VOR BIOPHARMA INC. (US) 2024-06-20 US claimed
US-3960844-A Preparation of 6-acylamino-2-methyl-2-halomethyl penams ELI LILLY AND COMPANY (US) 1976-06-01 US claimed
US-3953436-A 3,4-Dicarboxycephalosporins and derivatives ELI LILLY AND COMPANY (US) 1976-04-27 US claimed
US-3953437-A Process of preparing cephalosporanic acid ester derivatives YAMANOUCHI PHARMACEUTICAL CO., LTD. (JA) 1976-04-27 US claimed
US-3944545-A Process for preparing desacetoxycephalosporins ELI LILLY AND COMPANY (US) 1976-03-16 US claimed
US-3941853-A HIGH ENERGY EXPLOSIVE THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 1976-03-02 US claimed
US-3940248-A WATER SOLUBLE 8-HYDROXY-S-TRIAZOLO(B)PYRIDAZINE COMPOUNDS OTSUKA KAGAKU YAKUHIN KABUSHIKI KAISHA (JA) 1976-02-24 US claimed
US-3936442-A ANTIBIOTIC BAYER AKTIENGESELLSCHAFT (DT) 1976-02-03 US claimed
US-3936447-A 7-Acylamino-desacetoxy-cephalosporanic acid esters and their production BAYER AKTIENGESELLSCHAFT (DT) 1976-02-03 US claimed
US-3931235-A FROM THE ALKALIMETAL SALT OF 4-HYDROXY-6-METHYL-2-PYRONE AND A THIOLSULFONATE THE DOW CHEMICAL COMPANY (US) 1976-01-06 US claimed
US-3931140-A (H-gly-gly-tyr-ala)1 -somatostatin AMERICAN HOME PRODUCTS CORPORATION (US) 1976-01-06 US claimed