Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNJ1 | P48048 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.37 |
| ▸ | SYK | P43405 | 1/20 | 0.37 |
| ▸ | MMP12 | P39900 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 2/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | F10 | P00742 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL287239 | 0.87 | NPC1 (0.53) | KCNJ1NPC1MAPTRAB9APOLB | |
| SCHEMBL17633961 | 0.86 | KMT2A (0.51) | KCNJ1NPC1MAPTRAB9APOLB | |
| SCHEMBL287709 | 0.85 | NPC1 (0.49) | NPC1MAPTRAB9APOLBNPSR1 | |
| SCHEMBL27851990 | 0.80 | NPC1 (0.46) | NPC1MAPTRAB9APOLBNPSR1 | |
| SCHEMBL12824117 | 0.80 | NPC1 (0.57) | KCNJ1NPC1MAPTRAB9APOLB | |
| SCHEMBL28869852 | 0.79 | NPC1 (0.48) | NPC1MAPTRAB9APOLBNPSR1 | |
| SCHEMBL27851991 | 0.76 | POLB (0.51) | NPC1MAPTRAB9APOLBNPSR1 | |
| SCHEMBL30276673 | 0.75 | POLB (0.46) | NPC1MAPTRAB9APOLBNPSR1 | |
| SCHEMBL14544647 | 0.73 | MAPT (0.71) | NPC1MAPTRAB9APOLBNPSR1 | |
| SCHEMBL30276683 | 0.72 | MAPT (0.47) | NPC1MAPTRAB9APOLBNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018095795-A1 | PESTICIDALLY ACTIVE POLYCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2018-05-31 | — | — | WO | disclosed |