Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 5/20 | 0.92 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.70 |
| ▸ | MAOA | P21397 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | TSHR | P16473 | 3/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.53 |
| ▸ | MAOB | P27338 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | ELANE | P08246 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | RECQL | P46063 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1450113 | 0.96 | STAT3 (1.00) | STAT3ALDH1A1MAOAMAPTTSHR | |
| Napabucasin SCHEMBL29349770 | 0.83 | STAT3 (1.00) | STAT3ALDH1A1MAOAMAPTMAPK1 | |
| Napabucasin SCHEMBL1883845 | 0.83 | STAT3 (1.00) | STAT3ALDH1A1MAOAMAPTMAPK1 | |
| SCHEMBL10037450 | 0.83 | STAT3 (0.77) | STAT3ALDH1A1MAOAMAPTTSHR | |
| SCHEMBL20187648 | 0.82 | STAT3 (0.65) | STAT3ALDH1A1MAPTTDP1LMNA | |
| SCHEMBL7678888 | 0.81 | STAT3 (0.61) | STAT3ALDH1A1MAOAMAPTTSHR | |
| SCHEMBL20190492 | 0.81 | STAT3 (0.61) | STAT3ALDH1A1MAOAMAPTTDP1 | |
| SCHEMBL20187596 | 0.80 | STAT3 (0.60) | STAT3ALDH1A1MAOAMAPTTSHR | |
| SCHEMBL10037451 | 0.80 | STAT3 (0.71) | STAT3ALDH1A1MAOAMAPTTSHR | |
| SCHEMBL20188858 | 0.78 | STAT3 (0.65) | STAT3ALDH1A1MAOAMAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018096401-A1 | NEW NAPHTHO[2,3-B]FURAN DERIVATIVES | BAN HITOSHI (JP) | 2018-05-31 | — | — | WO | claimed |
| WO-2018096401-A1 | NEW NAPHTHO[2,3-B]FURAN DERIVATIVES | BAN HITOSHI (JP) | 2018-05-31 | — | — | WO | disclosed |