Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | GRK6 | P43250 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | ACLY | P53396 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20191214 | 0.83 | STAT3 (0.54) | STAT3ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL11122148 | 0.81 | HDAC4 (0.62) | ALDH1A1HDAC4HDAC2HDAC8POLB | |
| SCHEMBL20189157 | 0.79 | STAT3 (0.66) | STAT3ALDH1A1POLBGAASMN1; SMN2 | |
| SCHEMBL20187637 | 0.79 | STAT3 (0.66) | STAT3ALDH1A1POLBGAASMN1; SMN2 | |
| SCHEMBL20187544 | 0.78 | STAT3 (0.63) | STAT3ALDH1A1POLBGAABLM | |
| SCHEMBL20187585 | 0.78 | STAT3 (0.63) | STAT3ALDH1A1POLBGAASMN1; SMN2 | |
| SCHEMBL20187658 | 0.77 | STAT3 (0.58) | STAT3ALDH1A1POLBGAASMN1; SMN2 | |
| SCHEMBL20189094 | 0.74 | STAT3 (0.58) | STAT3ALDH1A1POLBGAASMN1; SMN2 | |
| SCHEMBL20187614 | 0.74 | STAT3 (0.58) | STAT3ALDH1A1POLBGAASMN1; SMN2 | |
| SCHEMBL20187669 | 0.73 | STAT3 (0.57) | STAT3ALDH1A1HDAC4HDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018096401-A1 | NEW NAPHTHO[2,3-B]FURAN DERIVATIVES | BAN HITOSHI (JP) | 2018-05-31 | — | — | WO | disclosed |