Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 6/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.56 |
| ▸ | MAPT | P10636 | 8/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MITF | O75030 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.36 |
| ▸ | MEN1 | O00255 | 5/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | APEX1 | P27695 | 3/20 | 0.35 |
| ▸ | RECQL | P46063 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20187614 | 0.96 | STAT3 (0.58) | STAT3ALDH1A1MAPTLMNAMITF | |
| SCHEMBL20196459 | 0.83 | STAT3 (0.67) | STAT3ALDH1A1MAPTLMNAMITF | |
| SCHEMBL20187585 | 0.83 | STAT3 (0.63) | STAT3ALDH1A1MAPTLMNAMITF | |
| SCHEMBL20188858 | 0.82 | STAT3 (0.65) | STAT3ALDH1A1MAPTLMNAMITF | |
| SCHEMBL20190492 | 0.80 | STAT3 (0.61) | STAT3ALDH1A1MAPTLMNAMITF | |
| SCHEMBL20189094 | 0.80 | STAT3 (0.58) | STAT3ALDH1A1MAPTLMNAMITF | |
| SCHEMBL20187622 | 0.79 | STAT3 (0.57) | STAT3ALDH1A1MAPTLMNAMITF | |
| SCHEMBL20187659 | 0.78 | STAT3 (0.56) | STAT3ALDH1A1GAAELANE | |
| SCHEMBL20187597 | 0.78 | STAT3 (0.56) | STAT3ALDH1A1MAPTLMNAHTT | |
| SCHEMBL1450113 | 0.77 | STAT3 (1.00) | STAT3ALDH1A1MAPTLMNAMITF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018096401-A1 | NEW NAPHTHO[2,3-B]FURAN DERIVATIVES | BAN HITOSHI (JP) | 2018-05-31 | — | — | WO | claimed |
| WO-2018096401-A1 | NEW NAPHTHO[2,3-B]FURAN DERIVATIVES | BAN HITOSHI (JP) | 2018-05-31 | — | — | WO | disclosed |