Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 5/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | USP8 | P40818 | 1/20 | 0.40 |
| ▸ | USP7 | Q93009 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20187669 | 0.96 | STAT3 (0.57) | STAT3ALDH1A1NPC1SMN1; SMN2RAB9A | |
| SCHEMBL20187648 | 0.80 | STAT3 (0.65) | STAT3ALDH1A1NPC1SMN1; SMN2RAB9A | |
| SCHEMBL20187646 | 0.80 | STAT3 (0.64) | STAT3ALDH1A1LMNARECQLMAPT | |
| SCHEMBL20187597 | 0.77 | STAT3 (0.56) | STAT3ALDH1A1NPC1SMN1; SMN2RAB9A | |
| SCHEMBL20188782 | 0.77 | STAT3 (0.50) | STAT3ALDH1A1NPC1SMN1; SMN2RAB9A | |
| SCHEMBL20191214 | 0.75 | STAT3 (0.54) | STAT3ALDH1A1NPC1RAB9AEPHX2 | |
| SCHEMBL20189157 | 0.75 | STAT3 (0.66) | STAT3ALDH1A1NPC1SMN1; SMN2RAB9A | |
| SCHEMBL20187637 | 0.75 | STAT3 (0.66) | STAT3ALDH1A1NPC1SMN1; SMN2RAB9A | |
| SCHEMBL20187585 | 0.74 | STAT3 (0.63) | STAT3ALDH1A1NPC1SMN1; SMN2RAB9A | |
| SCHEMBL20196459 | 0.74 | STAT3 (0.67) | STAT3ALDH1A1NPC1SMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018096401-A1 | NEW NAPHTHO[2,3-B]FURAN DERIVATIVES | BAN HITOSHI (JP) | 2018-05-31 | — | — | WO | claimed |