Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 6/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | TTR | P02766 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | BCL2 | P10415 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20187668 | 0.96 | STAT3 (0.56) | STAT3ALDH1A1TTRLMNAHSD17B10 | |
| SCHEMBL20191163 | 0.81 | STAT3 (0.66) | STAT3ALDH1A1LMNAHSD17B10KDM4E | |
| SCHEMBL20187544 | 0.79 | STAT3 (0.63) | STAT3ALDH1A1TTRLMNAHSD17B10 | |
| SCHEMBL20188858 | 0.78 | STAT3 (0.65) | STAT3ALDH1A1LMNAHSD17B10KDM4E | |
| SCHEMBL20187596 | 0.77 | STAT3 (0.60) | STAT3ALDH1A1LMNAHSD17B10KDM4E | |
| SCHEMBL20191216 | 0.77 | STAT3 (0.60) | STAT3ALDH1A1LMNAHSD17B10KDM4E | |
| SCHEMBL20196459 | 0.76 | STAT3 (0.67) | STAT3ALDH1A1TTRLMNAHSD17B10 | |
| SCHEMBL20187614 | 0.75 | STAT3 (0.58) | STAT3ALDH1A1TTRLMNAHSD17B10 | |
| SCHEMBL1450113 | 0.72 | STAT3 (1.00) | STAT3ALDH1A1TTRLMNAHSD17B10 | |
| SCHEMBL20190492 | 0.72 | STAT3 (0.61) | STAT3ALDH1A1TTRLMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018096401-A1 | NEW NAPHTHO[2,3-B]FURAN DERIVATIVES | BAN HITOSHI (JP) | 2018-05-31 | — | — | WO | claimed |
| WO-2018096401-A1 | NEW NAPHTHO[2,3-B]FURAN DERIVATIVES | BAN HITOSHI (JP) | 2018-05-31 | — | — | WO | disclosed |