Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 7/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | APEX1 | P27695 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | ELANE | P08246 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | PTP4A3 | O75365 | 1/20 | 0.35 |
| ▸ | GMNN | O75496 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20187622 | 0.96 | STAT3 (0.57) | STAT3ALDH1A1LMNAMAPTHSD17B10 | |
| SCHEMBL20187596 | 0.82 | STAT3 (0.60) | STAT3ALDH1A1LMNAMAPTHSD17B10 | |
| SCHEMBL20187614 | 0.80 | STAT3 (0.58) | STAT3ALDH1A1LMNAMAPTHSD17B10 | |
| SCHEMBL20191216 | 0.78 | STAT3 (0.60) | STAT3ALDH1A1LMNAMAPTHSD17B10 | |
| SCHEMBL20191163 | 0.77 | STAT3 (0.66) | STAT3ALDH1A1LMNAMAPTHSD17B10 | |
| SCHEMBL20188858 | 0.77 | STAT3 (0.65) | STAT3ALDH1A1LMNAMAPTHSD17B10 | |
| SCHEMBL20190492 | 0.77 | STAT3 (0.61) | STAT3ALDH1A1LMNAMAPTHSD17B10 | |
| SCHEMBL20187544 | 0.75 | STAT3 (0.63) | STAT3ALDH1A1LMNAMAPTHSD17B10 | |
| SCHEMBL20187568 | 0.73 | STAT3 (0.92) | STAT3ALDH1A1LMNAMAPTHSD17B10 | |
| SCHEMBL1882564 | 0.72 | STAT3 (0.69) | STAT3ALDH1A1LMNAMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018096401-A1 | NEW NAPHTHO[2,3-B]FURAN DERIVATIVES | BAN HITOSHI (JP) | 2018-05-31 | — | — | WO | disclosed |