Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 12/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20188214 | 1.00 | APLNR (0.49) | APLNR | |
| SCHEMBL23549413 | 1.00 | APLNR (0.49) | APLNR | |
| SCHEMBL18245771 | 0.85 | APLNR (0.49) | APLNR | |
| SCHEMBL20188590 | 0.83 | APLNR (0.49) | APLNR | |
| SCHEMBL20189014 | 0.83 | APLNR (0.49) | APLNR | |
| SCHEMBL18247096 | 0.83 | APLNR (0.43) | APLNR | |
| SCHEMBL18245727 | 0.83 | APLNR (0.43) | APLNR | |
| SCHEMBL18246161 | 0.83 | APLNR (0.43) | APLNR | |
| SCHEMBL22466703 | 0.81 | LMNA (0.41) | APLNR | |
| SCHEMBL20188099 | 0.76 | APLNR (0.38) | APLNR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3541792-A1 | TRIAZOLE FURAN COMPOUNDS AS AGONISTS OF THE APJ RECEPTOR | Amgen Inc. (US) | 2019-09-25 | — | — | EP | disclosed |
| WO-2018097944-A1 | TRIAZOLE FURAN COMPOUNDS AS AGONISTS OF THE APJ RECEPTOR | AMGEN INC. (US) | 2018-05-31 | — | — | WO | disclosed |