Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DUT | P33316 | 15/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20188094 | 0.86 | DUT (0.40) | DUTSMN1; SMN2MAPT | |
| SCHEMBL22723240 | 0.83 | DUT (0.55) | DUT | |
| SCHEMBL22723244 | 0.83 | DUT (0.55) | DUT | |
| SCHEMBL22723242 | 0.83 | DUT (0.55) | DUT | |
| SCHEMBL20187875 | 0.82 | DUT (0.44) | DUTSCN9A | |
| SCHEMBL18374309 | 0.82 | DUT (0.44) | DUTSCN9A | |
| SCHEMBL18374307 | 0.82 | DUT (0.44) | DUTSCN9A | |
| SCHEMBL20190545 | 0.78 | DUT (0.43) | DUTSMN1; SMN2KCNH2 | |
| SCHEMBL20189332 | 0.75 | DUT (0.65) | DUT | |
| SCHEMBL20187800 | 0.74 | DUT (0.54) | DUT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018098206-A1 | HYDANTOIN CONTAINING DEOXYURIDINE TRIPHOSPHATASE INHIBITORS | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2018-05-31 | — | — | WO | disclosed |