Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DUT | P33316 | 10/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20187944 | 0.86 | DUT (0.46) | DUTSMN1; SMN2MAPT | |
| SCHEMBL22723280 | 0.84 | DUT (0.56) | DUT | |
| SCHEMBL22723279 | 0.84 | DUT (0.56) | DUT | |
| SCHEMBL22723278 | 0.84 | DUT (0.56) | DUT | |
| SCHEMBL18374403 | 0.83 | DUT (0.40) | DUT | |
| SCHEMBL18374399 | 0.83 | DUT (0.40) | DUT | |
| SCHEMBL20351381 | 0.83 | DUT (0.40) | DUT | |
| SCHEMBL20187797 | 0.83 | DUT (0.40) | DUTSMN1; SMN2ALDH1A1 | |
| SCHEMBL20201755 | 0.75 | DUT (0.35) | DUT | |
| SCHEMBL20201751 | 0.75 | DUT (0.35) | DUT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018098206-A1 | HYDANTOIN CONTAINING DEOXYURIDINE TRIPHOSPHATASE INHIBITORS | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2018-05-31 | — | — | WO | disclosed |