Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DUT | P33316 | 12/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.37 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20196513 | 0.89 | DUT (0.48) | DUTSMN1; SMN2SCN9ASCN5A | |
| SCHEMBL20191217 | 0.83 | DUT (0.49) | DUT | |
| SCHEMBL20188135 | 0.83 | DUT (0.54) | DUT | |
| SCHEMBL20187699 | 0.82 | DUT (0.53) | DUT | |
| SCHEMBL20189248 | 0.81 | DUT (0.52) | DUT | |
| SCHEMBL20188278 | 0.76 | DUT (0.42) | DUTSMN1; SMN2 | |
| SCHEMBL20377769 | 0.76 | DUT (0.38) | DUTSCN9A | |
| SCHEMBL20190360 | 0.76 | DUT (0.49) | DUTALDH1A1 | |
| SCHEMBL20191175 | 0.75 | DUT (0.58) | DUT | |
| SCHEMBL20191176 | 0.75 | DUT (0.58) | DUT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018098206-A1 | HYDANTOIN CONTAINING DEOXYURIDINE TRIPHOSPHATASE INHIBITORS | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2018-05-31 | — | — | WO | disclosed |