Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DUT | P33316 | 10/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | PPARG | P37231 | 2/20 | 0.36 |
| ▸ | PPARA | Q07869 | 2/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
| ▸ | SLC5A7 | Q9GZV3 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20188108 | 0.88 | DUT (0.45) | DUTCYP2D6PPARGPPARAMTNR1A | |
| SCHEMBL20190547 | 0.86 | DUT (0.46) | DUT | |
| SCHEMBL20188455 | 0.85 | DUT (0.47) | DUTNPC1RAB9AMTNR1AAKR1C3 | |
| SCHEMBL21315531 | 0.83 | DUT (0.55) | DUT | |
| SCHEMBL21315533 | 0.83 | DUT (0.55) | DUT | |
| SCHEMBL20190338 | 0.82 | DUT (0.46) | DUTNPC1RAB9AMTNR1AAKR1C3 | |
| SCHEMBL20188045 | 0.81 | DUT (0.51) | DUTNPC1RAB9AMTNR1AAKR1C3 | |
| SCHEMBL22751566 | 0.77 | DUT (0.54) | DUT | |
| SCHEMBL20188224 | 0.76 | DUT (0.51) | DUTNPC1RAB9AMTNR1AAKR1C3 | |
| SCHEMBL20188526 | 0.74 | DUT (0.51) | DUTNPC1RAB9AMTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018098206-A1 | HYDANTOIN CONTAINING DEOXYURIDINE TRIPHOSPHATASE INHIBITORS | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2018-05-31 | — | — | WO | disclosed |
| WO-2018098204-A1 | 6-MEMBERED URACIL ISOSTERES | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2018-05-31 | — | — | WO | disclosed |