Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DUT | P33316 | 9/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.35 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | PLG | P00747 | 1/20 | 0.34 |
| ▸ | PLAU | P00749 | 1/20 | 0.34 |
| ▸ | PLAT | P00750 | 1/20 | 0.34 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20188455 | 0.92 | DUT (0.47) | DUTNPC1RAB9AMTNR1AAKR1C3 | |
| SCHEMBL21315534 | 0.82 | DUT (0.57) | DUT | |
| SCHEMBL21315538 | 0.82 | DUT (0.57) | DUT | |
| SCHEMBL20188149 | 0.82 | DUT (0.45) | DUTNPC1RAB9AMTNR1AAKR1C3 | |
| SCHEMBL20188045 | 0.79 | DUT (0.51) | DUTNPC1RAB9AMTNR1AAKR1C3 | |
| SCHEMBL20188224 | 0.78 | DUT (0.51) | DUTNPC1RAB9AMTNR1AAKR1C3 | |
| SCHEMBL20191202 | 0.77 | DUT (0.49) | DUTKCNH2 | |
| SCHEMBL20187971 | 0.77 | DUT (0.49) | DUTNPC1RAB9AMTNR1AKAT6A | |
| SCHEMBL20188526 | 0.76 | DUT (0.51) | DUTNPC1RAB9AMTNR1AKAT6A | |
| SCHEMBL21315520 | 0.73 | DUT (0.58) | DUT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018098204-A1 | 6-MEMBERED URACIL ISOSTERES | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2018-05-31 | — | — | WO | disclosed |