Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OGT | O15294 | 3/20 | 0.52 |
| ▸ | FLT3 | P36888 | 2/20 | 0.49 |
| ▸ | CA1 | P00915 | 6/20 | 0.48 |
| ▸ | CA2 | P00918 | 6/20 | 0.48 |
| ▸ | CA5A | P35218 | 5/20 | 0.48 |
| ▸ | CA5B | Q9Y2D0 | 5/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 11/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 5/20 | 0.47 |
| ▸ | CA12 | O43570 | 3/20 | 0.46 |
| ▸ | CA9 | Q16790 | 3/20 | 0.46 |
| ▸ | GSK3B | P49841 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | SNCA | P37840 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12573356 | 0.87 | FLT3 (0.66) | OGTFLT3CA1CA2CA5A | |
| SCHEMBL27881785 | 0.85 | OGT (0.65) | OGTFLT3CA1CA2CA5A | |
| SCHEMBL18737325 | 0.83 | FLT3 (0.69) | OGTFLT3CA1CA2CA5A | |
| SCHEMBL2053754 | 0.80 | CA2 (0.61) | OGTFLT3CA1CA2CA5A | |
| SCHEMBL2019795 | 0.79 | APP (0.53) | OGTFLT3CA1CA2CA5A | |
| SCHEMBL13453289 | 0.74 | FLT3 (0.81) | OGTFLT3CA1CA2CA5A | |
| SCHEMBL2020551 | 0.73 | APP (0.55) | OGTCA1CA2CA5ACA5B | |
| SCHEMBL16408119 | 0.73 | APP (0.41) | OGTGSK3B | |
| SCHEMBL28236667 | 0.73 | NOTUM (0.41) | OGTFLT3PTGS2PTGS1 | |
| SCHEMBL29199654 | 0.72 | FLT3 (0.72) | OGTFLT3PTGS2PTGS1GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110158907-A1 | DIPHENYL-HETEROARYL DERIVATIVES AND THEIR USE FOR BINDING AND IMAGING AMYLOID PLAQUES | THE TRUSTEES OF THE UNIVERISTY OF PENNSYLVANIA (US) | 2011-06-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110158907-A1 | DIPHENYL-HETEROARYL DERIVATIVES AND THEIR USE FOR BINDING AND IMAGING AMYLOID PLAQUES | APP, APBA1, BACE2 | OGT 1596/4885FLT3 2894/4885CA1 2948/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.