SCHEMBL20189376

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL9164640	0.80	EPHX2 (0.49)	EPHX2DDB1CRBNGAAMEN1
	SCHEMBL20189142	0.78	EPHX2 (0.47)	EPHX2DDB1CRBNGAAMAPK1
	SCHEMBL28757730	0.78	EPHX2 (0.47)	EPHX2DDB1CRBNGAATSHR
	SCHEMBL8009140	0.78	EPHX2 (0.47)	EPHX2DDB1CRBNCYP19A1GAA
	SCHEMBL840894	0.78	EPHX2 (0.47)	EPHX2DDB1CRBNGAAMAPK1
	SCHEMBL9850086	0.78	DDB1 (0.69)	EPHX2DDB1CRBNGAATSHR
	SCHEMBL1011633	0.78	DDB1 (0.69)	EPHX2DDB1CRBNGAATSHR
	SCHEMBL8136911	0.77	POLB (0.65)	USP2CYP19A1HTR2CMAPK1TSHR
	SCHEMBL7436022	0.76	PRMT5 (0.55)	USP2CYP19A1MAPK1TSHRSMN1; SMN2
	SCHEMBL9850110	0.76	DDB1 (0.67)	EPHX2DDB1CRBNGAAMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.