SCHEMBL20189497

SCHEMBL20189497

[CH2]CC[Si](C)(C)CCCC.[LiH]

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20189660 0.97 TSHR (0.32) LMNATSHR
SCHEMBL7737553 0.86 TSHR (0.32) LMNATSHR
SCHEMBL11418684 0.83 TSHR (0.43) LMNATSHR
SCHEMBL8458241 0.82 TSHR (0.33) TSHR
SCHEMBL8458528 0.82 TSHR (0.33) TSHR
SCHEMBL5846089 0.80
SCHEMBL2804545 0.78
SCHEMBL11431867 0.77 TSHR (0.44) LMNATSHR
SCHEMBL27923946 0.77 TSHR (0.38) LMNATSHR
SCHEMBL27093902 0.75 TSHR (0.50) LMNATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3544720-A1 POROUS MEMBRANES INCLUDING PENTABLOCK COPOLYMERS AND METHOD OF MAKING THE SAME 3M Innovative Properties Company (US) 2019-10-02 EP disclosed
WO-2018097988-A1 POROUS MEMBRANES INCLUDING PENTABLOCK COPOLYMERS AND METHOD OF MAKING THE SAME 3M INNOVATIVE PROPERTIES COMPANY (US) 2018-05-31 WO disclosed