SCHEMBL20189660

SCHEMBL20189660

[CH2]CC[Si](C)(C)CCCC

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.32
LMNA P02545 1/20 0.32
THRB P10828 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20189497 0.97 LMNA (0.30) TSHRLMNA
SCHEMBL7737553 0.89 TSHR (0.32) TSHRLMNATHRB
SCHEMBL11418684 0.85 TSHR (0.43) TSHRLMNATHRB
SCHEMBL8458528 0.84 TSHR (0.33) TSHRTHRB
SCHEMBL8458241 0.84 TSHR (0.33) TSHRTHRB
SCHEMBL5846089 0.82
SCHEMBL2804545 0.80
SCHEMBL11431867 0.79 TSHR (0.44) TSHRLMNATHRB
SCHEMBL27923946 0.79 TSHR (0.38) TSHRLMNATHRB
SCHEMBL27093902 0.77 TSHR (0.50) TSHRLMNATHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3545023-A1 PENTABLOCK COPOLYMERS 3M Innovative Properties Company (US) 2019-10-02 EP disclosed
WO-2018098023-A1 PENTABLOCK COPOLYMERS 3M INNOVATIVE PROPERTIES COMPANY (US) 2018-05-31 WO disclosed