Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | PTPRA | P18433 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.37 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.37 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.37 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.37 |
| ▸ | PYGL | P06737 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.37 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20190841 | 0.91 | GAA (0.39) | GAAPTPRAMAPTSMN1; SMN2CYP1A2 | |
| SCHEMBL20188296 | 0.90 | GAA (0.39) | GAAPTPRAMAPTSMN1; SMN2CYP1A2 | |
| SCHEMBL20189047 | 0.90 | GPR139 (0.44) | GAAPYGLPOLB | |
| SCHEMBL20188659 | 0.90 | MAPT (0.41) | GAAPTPRAMAPTSMN1; SMN2CYP1A2 | |
| SCHEMBL20187735 | 0.89 | PTPRA (0.40) | GAAPTPRAMAPTSMN1; SMN2CYP1A2 | |
| SCHEMBL22457666 | 0.89 | GAA (0.38) | GAAPTPRAMAPTSMN1; SMN2CYP1A2 | |
| SCHEMBL20188367 | 0.89 | CA2 (0.39) | GAAPTPRASMN1; SMN2CYP1A2CYP2D6 | |
| SCHEMBL20188026 | 0.88 | MAPT (0.38) | GAAPTPRAMAPTSMN1; SMN2CYP1A2 | |
| SCHEMBL20190022 | 0.88 | PTPRA (0.39) | GAAPTPRAMAPTSMN1; SMN2CYP1A2 | |
| SCHEMBL20188572 | 0.88 | PTPRA (0.39) | GAAPTPRASMN1; SMN2GRIN2DGRIN3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018098344-A1 | PRODRUGS OF LANICEMINE AND THEIR METHOD OF USE | BIOHAVEN PHARMACEUTICAL HOLDING COMPANY LTD. (US) | 2018-05-31 | — | — | WO | disclosed |