Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DUT | P33316 | 5/20 | 0.36 |
| ▸ | PPARG | P37231 | 4/20 | 0.34 |
| ▸ | PPARA | Q07869 | 4/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20190547 | 0.85 | DUT (0.46) | DUTSMN1; SMN2 | |
| SCHEMBL20188511 | 0.85 | DUT (0.46) | DUT | |
| SCHEMBL22723299 | 0.84 | DUT (0.49) | DUT | |
| SCHEMBL20190509 | 0.84 | DUT (0.49) | DUT | |
| SCHEMBL22751590 | 0.78 | DUT (0.49) | DUT | |
| SCHEMBL20190545 | 0.77 | DUT (0.43) | DUTSMN1; SMN2 | |
| SCHEMBL20188108 | 0.76 | DUT (0.45) | DUTPPARGPPARA | |
| SCHEMBL20188149 | 0.74 | DUT (0.45) | DUTPPARGPPARA | |
| SCHEMBL22723288 | 0.73 | DUT (0.58) | DUT | |
| SCHEMBL20188508 | 0.73 | DUT (0.58) | DUT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018098206-A1 | HYDANTOIN CONTAINING DEOXYURIDINE TRIPHOSPHATASE INHIBITORS | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2018-05-31 | — | — | WO | disclosed |