Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DUT | P33316 | 7/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.34 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.34 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.34 |
| ▸ | LPAR5 | Q9H1C0 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.32 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.32 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20190547 | 0.85 | DUT (0.46) | DUTKCNH2SLC6A9APOBEC3AHTT | |
| SCHEMBL20188455 | 0.85 | DUT (0.47) | DUTKCNH2 | |
| SCHEMBL20191201 | 0.81 | DUT (0.60) | DUT | |
| SCHEMBL22723273 | 0.81 | DUT (0.60) | DUT | |
| SCHEMBL20189268 | 0.81 | DUT (0.52) | DUTKCNH2SLC6A9SMN1; SMN2HRH1 | |
| SCHEMBL20188158 | 0.80 | DUT (0.47) | DUTKCNH2SLC6A9SMN1; SMN2ADRB3 | |
| SCHEMBL20188104 | 0.80 | DUT (0.52) | DUTKCNH2SLC6A9SMN1; SMN2HRH1 | |
| SCHEMBL20191204 | 0.78 | DUT (0.52) | DUTKCNH2SLC6A9SMN1; SMN2HRH1 | |
| SCHEMBL20190338 | 0.77 | DUT (0.46) | DUTKCNH2 | |
| SCHEMBL22751606 | 0.73 | DUT (0.56) | DUT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018098206-A1 | HYDANTOIN CONTAINING DEOXYURIDINE TRIPHOSPHATASE INHIBITORS | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2018-05-31 | — | — | WO | disclosed |