Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13164724 | 0.89 | LMNA (0.46) | LMNAL3MBTL1MAPK1MEN1KMT2A | |
| SCHEMBL21350416 | 0.86 | MEN1 (0.41) | LMNAL3MBTL1MAPK1MEN1KMT2A | |
| SCHEMBL13184561 | 0.81 | LMNA (0.41) | LMNAL3MBTL1MAPK1MEN1KMT2A | |
| SCHEMBL11978610 | 0.81 | LMNA (0.41) | LMNAL3MBTL1MAPK1MEN1KMT2A | |
| SCHEMBL14458150 | 0.81 | MAPK1 (0.44) | LMNAL3MBTL1MAPK1MEN1KMT2A | |
| SCHEMBL24642948 | 0.81 | LMNA (0.41) | LMNAL3MBTL1MAPK1MEN1KMT2A | |
| SCHEMBL24212836 | 0.80 | LMNA (0.43) | LMNAL3MBTL1MAPK1MEN1KMT2A | |
| SCHEMBL13373655 | 0.79 | LMNA (0.40) | LMNAL3MBTL1MAPK1MEN1KMT2A | |
| SCHEMBL8404981 | 0.78 | GAA (0.46) | LMNAL3MBTL1MAPK1MEN1KMT2A | |
| SCHEMBL19662091 | 0.78 | MMP1 (0.42) | LMNAL3MBTL1MAPK1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9981043-B2 | Analgesic conjugates | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2018-05-29 | — | — | US | disclosed |