Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | BLM | P54132 | 3/20 | 0.45 |
| ▸ | USP2 | O75604 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | TGM2 | P21980 | 1/20 | 0.36 |
| ▸ | FPR2 | P25090 | 4/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.33 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 2/20 | 0.33 |
| ▸ | PLEC | Q15149 | 1/20 | 0.33 |
| ▸ | AVPR2 | P30518 | 2/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15483660 | 0.88 | MEN1 (0.45) | MEN1KMT2ABLMUSP2POLB | |
| SCHEMBL15704723 | 0.85 | MEN1 (0.61) | MEN1KMT2ABLMUSP2POLB | |
| SCHEMBL20192210 | 0.81 | ABCB1 (0.55) | MEN1KMT2ABLMUSP2POLB | |
| SCHEMBL20192126 | 0.81 | MEN1 (0.38) | MEN1KMT2ABLMUSP2POLB | |
| SCHEMBL18637030 | 0.77 | ERN1 (0.38) | MEN1KMT2ABLMUSP2POLB | |
| SCHEMBL17409220 | 0.73 | MEN1 (0.59) | MEN1KMT2ABLMUSP2POLB | |
| SCHEMBL12763951 | 0.72 | POLB (0.50) | MEN1KMT2ABLMUSP2POLB | |
| SCHEMBL19494774 | 0.72 | USP2 (0.53) | MEN1KMT2ABLMUSP2POLB | |
| SCHEMBL9001017 | 0.72 | MEN1 (0.57) | MEN1KMT2ABLMUSP2POLB | |
| SCHEMBL18637031 | 0.72 | ERN1 (0.35) | MEN1KMT2ABLMUSP2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9981934-B2 | Enzyme-specific fluorescent compound capable of being retained in cells | THE UNIVERSITY OF TOKYO (JP) | 2018-05-29 | — | — | US | disclosed |